What is clear is that women and men can react so differently to both pain and pain medications that, as the McGill University pain geneticist Jeffrey Mogil only half-jokingly puts it, we may someday have pink pills for women and blue pills for men.
Here's what we do know. Clinically, women are both more likely to get chronic painful conditions that can afflict either sex and to report greater pain than men with the same condition, according to studies over the past 15 years. (Women also have more acute pain than men even after the same surgeries, such as wisdom tooth extraction, gall bladder removal, hernia repair and hip and knee surgery.)
In 2008, when researchers looked at prevalence rates in 10 developed and seven developing countries, in a sample that included more than 85,000 people, they discovered that the prevalence of any chronic pain condition was 45% among women, versus 31% among men.
You can read the entire article at Wall Street Journal.